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  • Imported Gestational Malaria

    Pregnant women can develop malaria in non-endemic areas, even when they are far removed from malaria exposure both geographically and temporally.

  • ID Consultation Leads to Reduced Mortality from Gram-Negative Bacteremia

    A multicenter, retrospective cohort study on patients with gram-negative bacteremia found infectious diseases consultation was associated with a 40% decrease in 30-day mortality.

  • 2024 Resolution: Not to Be Replaced by a Machine

    Chatbots, such as ChatGPT, are thought to have potential to eventually replace some straightforward infectious disease consultations. However, current technology does not yet instill confidence that the use of chatbots will be adequately accurate or safe for complex patient care. In addition, philosophical and ethical constraints raise doubt about the value of replacing specialist physician consultations.

  • Vonoprazan Fumarate Tablets (Voquezna)

    The U.S. Food and Drug Administration has approved vonoprazan for the treatment of all grades of erosive esophagitis. Vonoprazan is a potassium-competitive acid blocker that originally was approved in 2022 for use in combination with amoxicillin or with amoxicillin and clarithromycin for the treatment of Helicobactor pylori infection.

  • Calling ED Boarding a Public Health Crisis, ACEP Pushes Policymakers to Act

    Too many EDs are bursting at the seams with patients who have been admitted but languish in the emergency setting for hours, days, or even weeks before they are moved to an inpatient bed. That is the message the American College of Emergency of Physicians is urgently sending to policymakers, saying the situation with ED boarding has become a public health crisis.

  • Treatable Causes of Rapidly Progressive Dementias

    Many cases of rapidly progressive dementia are caused by prion diseases and have no effective treatments. But, with the greater awareness of the presentation for autoimmune encephalitis, these disorders make up an increasing percentage of presenting cases and can be aggressively and successfully treated. The STAM3P score helps to identify potentially treatable cases of this disorder.

  • Pediatric Burn Care: Strategies for Identification and Treatment

    Pediatric burn injuries, especially minor, are an essential part of caring for children. Classification of the depth of injury, recognition of nonaccidental trauma, and appropriate care are all critical aspects of management. The authors comprehensively review pediatric burn care.

  • Apixaban Dose in Atrial Fibrillation Patients with Chronic Kidney Disease

    A large nationwide health systems database study comparing 5 mg apixaban vs. 2.5 mg twice daily in patients with stage 4/5 chronic kidney disease not on dialysis shows that the 5 mg dose increases the risk of bleeding compared to 2.5 mg without any improvement in the risk of stroke, systemic emboli, or death.

  • Has the Pandemic Increased the Likelihood of Bioterror?

    Has the global disruption and widespread death caused by SARS-CoV-2 made biological pathogens a more compelling and/or attainable goal by bioterrorists? There are differing views on this question, although all can agree that this is the last thing healthcare workers need to deal with.

  • Slow-Wave Sleep and Risk of Dementia

    In this long-term observational study of sleep efficiency in the Framingham Heart Study population, researchers found a strong correlation between a decline in duration of slow-wave sleep during aging and the risk of incident dementia from all causes. However, a direct cause-and-effect relationship cannot be determined from this observational study.